Given the understanding that considering equity, diversity and inclusion improves research outcomes by making results more ethical, rigorous, and socially relevant, a growing number of grant programs have added requirements for consideration of sex, gender and diversity in the research design. Gender-based Analysis Plus (GBA+) is an analytical approach that offers the needed tools for ensuring that principles of equity, diversity, and inclusion are applied in the research design, including methods, data analysis, interpretation of results, and knowledge mobilization or translation. GBA+ can support researchers in any discipline to examine how, and at what stage of the research, identify factors such as sex, gender, sexual orientation, race, ethnicity, religion, age, ability, and intersections between these factors have an impact. This presentation provides practical recommendations for how researchers can use a GBA+ analysis to strengthen the research design by asking clear and concise questions. It will also provide tangible examples of how to include GBA+ rationale in grant applications once the analysis is complete.